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Aging Overview

External factors

External factors: Resveratrol
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Glioma
Experimental category: L
Tissue type: --
Cell name: U87 MG,U-118 MG
PMID: 21481687
Experiment: SA-β-gal activity assay//Cell morphological analysis
Description: Resveratrol induced dramatic changes in cell volume and cell morphology in both U87 and U118 cells. Specifically, resveratrol transformed spindle-shaped glioma cells to enlarged and irregular flattenshaped ones.SA-β-gal was detected in these hypertrophic cells.



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Regulatory relationship

Target gene: UH2B
R-EF-Target gene: Downregulation
Official symbol(s): UH2B
Target gene experiment: Western blot
Target gene description: Resveratrol inhibited uH2B within 4 h in a dose-dependent manner.


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Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.




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