External factors
| External factors: |
CRT0063465 |
| Category: |
Chemical compounds |
| Experiment: |
Southern blot |
| Description: |
Strikingly, however, despite the lack of effects observed on total cellular telomerase activity by CRT0063465, hypoglycemic erosion of telomeres was blocked in the presence of the compound at both 100 nM and 10 nM. |
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Regulatory relationship
| Official symbol(s): |
PGK1//PARK7 |
| Target gene experiment: |
Co-IP |
| Target gene description: |
For PGK1, 10 nM CRT0063465 increased telomere association under physiological glucose conditions.For DJ1, compound treatment did not significantly affect telomere association under physiological conditions. |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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