External factors
| Category: |
Chemical compounds |
| Phenotype: |
Gynaecological Cancer |
| Experiment: |
MTT assay//TRAP assay |
| Description: |
Cell proliferation after 72 h of incubation was assessed by the MTT assay. Both the cell lines demonstrated reduced proliferation with increasing concentrations of RTI. |
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Regulatory relationship
| R-EF-Target gene:
|
Upregulation//Upregulation |
| Official symbol(s): |
P53//P21 |
| Target gene experiment: |
RT-PCR |
| Target gene description: |
In HEC-1 cells, the expression of TP53 increased with ddI (P< 0.001).The expression of p21 increased with ddI (P< 0.001). |
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Aging network
Annotation:
The green line represents Upregulation.
The purple line represents Downregulation.
The orange line represents Activation.
The yellow line represents Inhibition.
The gray line represents Unclear.
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