| Gene name: | POLR3A |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | fibroblast |
| Gene ID: | 11128 |
| Category: | protein coding |
| Phenotype: | Wiedemann-Rautenstrauch syndrome (WRS) |
| Experimental category: | L |
| PMID: | 32976914 |
| Experiment: | SA-β-gal activity assay//Western blot//Immunostaining//Telomere length assay |
| Description: | Beta-galactosidase staining (pH 6) was evident at PD 45 in controls, at PD 27 in HGPS, and at PD 36 in WRS fibroblasts (A). Nuclear morphology analyzed by Lamin A immunostaining is shown for HGPS cells (C), control cells (D), and WRS (E) cells. Relative telomere length is shown in (G). |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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