| Gene name: | MTX2 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | Primary Fibroblast |
| Gene ID: | 10651 |
| Category: | protein coding |
| Phenotype: | Mandibuloacral dysplasia |
| Experimental category: | HL |
| PMID: | 32917887 |
| Experiment: | SA-β-gal activity assay |
| Description: | Senescence was examined in cells by a senescence associated β-galactosidase assay following the manufacturer’s protocol (Cell Signaling #9860). |
| Target gene: | MTX1 |
| Official symbol(s): | MTX1 |
| R-AG-Target gene: | Upregulation |
| Subcategory: | Unclear |
| Target gene experiment: | Western blot |
| Target gene description: | Immunoblot analysis of MTX2 and other outer and inner mitochondrial membrane proteins of whole-cell extracts from healthy control (WT) and patients’ (MADM2, MADM3)fibroblasts. Actin or REVERT total proteins were used as loading controls. n = 3 independent experiments for MTX2, TOMM22, SAMM50, CHCHD3 and n = 2 independent experiments for MTX1, VDAC2, TOMM40. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
Loading,please wait...