| Gene name: | BMP2 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | RasV12 |
| Experiment: | SA-β-gal activity assay//Knockdown |
| Description: | Bmp2-knocked-down RasV12 cells escaped from senescence with decreased number of SA-βgal(+) cells compared to RasV12 cells.The cells showed increased number of SA-βgal(+) cells in dose-dependent manner,even to the level of RasV12 cells when rBMP2 was at 200 ng/mL. |
| Target gene: | SMAD1//SMAD6 |
| Official symbol(s): | SMAD1//SMAD6 |
| R-AG-Target gene: | Upregulation//Upregulation |
| Subcategory: | Methylation |
| Target gene experiment: | Knockdown//Western blot//CHIP-seq |
| Target gene description: | Smad1 target genes upregulated most by rBMP exposure included Smad6, which was upregulated by 4.5-fold in MEF. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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