| Gene name: | MALAT1 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | Foreskin |
| Cell name: | Fibroblast |
| Experiment: | SA-β-gal activity assay |
| Description: | The ratio of senescent cells was markedly greater following UVB irradiation (74.4%) compared with cells that had not been exposed to irradiation (15.7%).In addition, the ratio of senescent cells was significantly lower following intervention with MALAT1 siRNA (52.1%) compared with the UVB irradiation group. |
| Regulatory pathway: | ERK-MAPK |
| R-AG-Pathway: | -- |
| Official symbol(s): | MAPK1 |
| Pathway experiment: | Western blot |
| Pathway description: | MALAT1 siRNA inhibited UVB-induced ERK phosphorylation. |
Annotation:
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