| Gene name: | TERC |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | 2BS |
| Experiment: | SA-β-gal activity assay//Immunostaining |
| Description: | hTERC-53 overexpressing cells showed a significantly faster senescence rate. Full length hTERC overexpressing cells also showed a similar phenotype, even though to a lesser extent, possibly the result of hTERC-53 accumulation due to overexpression of the full length RNA. Expression of hTERC-53r led to minor downregulation of the expression levels of the senescence markers such as p-AMPK and p16, and removal of the inhibitory modification of MnSOD. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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