| Gene name: | NEK6 |
| Aging type: | Prevent |
| Aging characteristic: | Others |
| Tissue type: | -- |
| Cell name: | IMR-90,EJ |
| Experiment: | SA-β-gal activity assay |
| Description: | While EJ-vector control cells became flattened and enlarged after p53 expression, EJ-Nek6 cells maintained normal morphology and grew continuously.In addition, whereas SA β-gal activity was significantly increased in EJ control cells starting 4 days after p53 expression, and a majority of EJ control cells showed SA β-gal activity at 6 day later, SA β-gal activity was significantly reduced in EJ-Nek6 cells indicating that the onset of p53- induced senescence was suppressed by Nek6 overexpression. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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