| Gene name: | PSMD14 |
| Aging type: | Prevent |
| Aging characteristic: | Others |
| Tissue type: | -- |
| Cell name: | H1299,HeLa,hTERT-HMEC1 |
| Experiment: | SA-β-gal activity assay//Knockdown//Flow cytometry |
| Description: | The cell cycle was arrested at the G0-G1 phase in PSMD14 knockdown cells. A significant increase of SA-β-Gal positive cells was observed in PSMD14 knockdown cells (52%). |
| Target gene: | CDK1//CYCLIN B//CDC25C |
| Official symbol(s): | CDK1//CYCLIN B//CDC25C |
| R-AG-Target gene: | Downregulation//Downregulation//Downregulation |
| Subcategory: | Phosphorylation |
| Target gene experiment: | Western blot |
| Target gene description: | Three days post-transfection with PSMD14 siRNA,the levels of cyclin B1, CDK1 and CDC25C were decreased to 6%, 33% and 30% of the control level(NT siRNA knockdown sample), respectively (from 30%, 64% and 62% of NT siRNA control, respectively at 2 days of knockdown). |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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