| Gene name: | BCL6 |
| Aging type: | Prevent |
| Aging characteristic: | Others |
| Tissue type: | -- |
| Cell name: | MEF |
| Experiment: | Survival curve |
| Description: | Importantly, when expressed in primary MEFs of FVB genetic background (at 37°C), BCL6 was very efficient in inhibiting both spontaneous senescence and premature senescence induced by a RASV12oncogene . |
| Target gene: | CYCLIN D1 |
| Official symbol(s): | CYCLIN D1 |
| R-AG-Target gene: | Upregulation |
| Subcategory: | Unclear |
| Target gene experiment: | Western blot |
| Target gene description: | The cyclin D1 protein level is up-regulated by BCL6 in three different cell types.This up-regulation of cyclin D1 is at the level of transcription, as cyclin D1 mRNA was also increased by BCL6 in MEFs. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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