| Gene name: | WRN |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | Embryo |
| Cell name: | MEF |
| Gene ID: | 7486 |
| Category: | protein coding |
| Phenotype: | Werner syndrome |
| Experimental category: | L |
| PMID: | 16264192 |
| Experiment: | Giemsa staining |
| Description: | After ～2 mo in culture, several foci emerged among 8 × 106 senescent G5 mTerc-/- Wrn-/- MEFs at a frequency of ～1.4 × 10-5.Under identical culture conditions, foci were not detected in senescent cultures of ～5 × 107 G5 mTerc-/- Wrn+/+ and ～2.5 × 107 G5 mTerc-/- Wrn+/- MEFs. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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