| Gene name: | TERT |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | WS,Fibroblast |
| Gene ID: | 7015 |
| Category: | protein coding |
| Phenotype: | Werner syndrome |
| Experimental category: | HL |
| PMID: | 24749076 |
| Experiment: | Immunostaining//Western blot//Southern Blot |
| Description: | The expression of hTERT in WS MSCs appears to rescue senescence through reduction of the p16 level (but not of p53/p21) and the DNA damage marker γH2AX.Longer telomere length was found in WS-MSCtert, but not in WS-MSCp53i,suggesting a rescue of the accelerated telomere attrition by telomerase. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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