| Gene name: | TINF2 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | Embryo |
| Cell name: | TIN2+/+,TIN2+/DC-cond,TIN2+/+ mTR-/-,TIN2+/DCmTR-/-MEF |
| Gene ID: | 26277 |
| Category: | protein coding |
| Phenotype: | Dyskeratosis congenita |
| Experimental category: | HL |
| PMID: | 24449270 |
| Experiment: | SA-β-gal activity assay//Knockdown//FISH |
| Description: | Furthermore, morphological examination and staining for β-galactosidase showed evidence of senescence in a small fraction of the TIN2+/DC Mtr-/- cells.Q-FISH measurements indicated that at a comparable PD, both TIN2+/DC mTR-/-MEFs had sustained greater telomere shortening than the TIN2+/+ mTR-/- MEFs, with the second TIN2+/DC mTR-/- MEF line showing the greatest reduction in mean telomere length. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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