| Gene name: | TP53 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | HCT116 |
| Gene ID: | 7157 |
| Category: | protein coding |
| Phenotype: | Colorectal cancer |
| Experimental category: | L |
| PMID: | 26099456 |
| Experiment: | SA-β-gal activity assay//Knockdown |
| Description: | HCT116 p53+/+ cells were much more vulnerable to premature senescence induced by ionizing radiation than p53?/? cells.It is apparent that signals secreted by irradiated p53+/+ cells were more effective in inducing senescence in p53?/? bystander cells than were those from p53?/? in their own bystanders. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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