| Gene name: | KRAS |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | DLD1(KRAS wt/mut),DWT7(wt/-) |
| Gene ID: | 3845 |
| Category: | protein coding |
| Phenotype: | Lung cancer |
| Experimental category: | L |
| PMID: | 24648348 |
| Experiment: | SA-β-gal activity assay//DAPI staining |
| Description: | In an isogenic model, KRAS wild-type cells were sensitive to treatment with erlotinib alone , with the induction of premature cellular senescence accounting for at least some of the effect. In contrast, erlotinib-treated KRAS-mutant cells were resistant to senescence induction. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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