| Gene name: | RB1 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | MSC |
| Gene ID: | 5925 |
| Category: | protein coding |
| Phenotype: | Retinoblastoma |
| Experimental category: | L |
| PMID: | 27124644 |
| Experiment: | SA-β-gal activity assay//Flow cytometry |
| Description: | In samples with silenced RB1, the percentage of cells in S-phase is lower than the unirradiated wild type MSCs. In cells with down-regulated RB1, we observed a significant reduction of clones in basal condition vs. controls. This agrees with the high levels of DNA damage and senescence. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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