| Gene name: | POT1 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | HT-1080,IMR-90 |
| Experiment: | Knockdown//SA-β-gal activity assay//Cell morphological analysis |
| Description: | Microscopic examination revealed a fraction of the hPot1 knockdown HT1080 cells with senescent phenotypes (not shown)microscopic examination revealed a fraction of the hPot1 knockdown HT1080 cells with senescent phenotypes (not shown).The Pot1 shRNA elicited a more severe senescent phenotype in these cells; many cells exhibited an enlarged and flattened morphology and stained strongly positive for β-galactosidase (β-gal), a marker of senescence. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
Loading,please wait...