| Gene name: | SOD1 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | Mammary Gland |
| Cell name: | Mammary epithelial cell |
| Gene ID: | 6647 |
| Category: | protein coding |
| Phenotype: | Breast cancer |
| Experimental category: | L |
| PMID: | 31222103 |
| Experiment: | Western blot//Knockdown//SA-β-gal activity assay//Immunohistochemistry |
| Description: | We found an increase in β-gal staining in the SOD1+/?/ErbB2 cells .Using p53 and p16 as markers of senescence, we found a significant increase in both markers in the SOD1?/?ErbB2 mammary glands. To confirm that senescence was induced in the epithelial cells, we performed immunohistochemistry of p16 and found a significant increase in p16 in the SOD1?/?/ErbB2 mammary glands. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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