| Gene name: | TERF2 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | SH-SY5Y |
| Gene ID: | 7014 |
| Category: | protein coding |
| Phenotype: | Neuroblastoma |
| Experimental category: | L |
| PMID: | 16539655 |
| Experiment: | SA-β-gal activity assay//BrdU assay |
| Description: | DN-TRF2 expression in neuroblastoma cells resulted in a significant reduction in their proliferation as indicated by a decrease of BrdU incorporation, limited growth rate and induction of expression of β-galactosidase. |
| Target gene: | P21//P53 |
| Official symbol(s): | P21//P53 |
| R-AG-Target gene: | Upregulation//Upregulation |
| Subcategory: | Unclear |
| Target gene experiment: | Western blot |
| Target gene description: | Levels of p21 and p53 were increased by more than 10-fold in neuroblastoma cells expressing DN-TRF2. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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