| Gene name: | POT1 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | IMR-90 |
| Experiment: | SA-β-gal activity assay |
| Description: | A premature senescent phenotype was observed in IMR90 cells expressing POT1-RNAi, as assayed by SA-β-Gal staining. |
| Target gene: | TRF2 |
| Official symbol(s): | TERF2 |
| R-AG-Target gene: | -- |
| Subcategory: | Unclear |
| Target gene experiment: | qPCR//Western blot//SA-β-gal activity assay |
| Target gene description: | The expression of POT1 decreased the loss of telomeric overhang induced by TRF2ΔBΔM.(B) POT1 blocked the senescent phenotype induced by TRF2ΔBΔM. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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