| Gene name: | MTDH |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | LNCaP,C4-2B |
| Gene ID: | 92140 |
| Category: | protein coding |
| Phenotype: | Prostate cancer |
| Experimental category: | L |
| PMID: | 28923415 |
| Experiment: | SA-β-gal activity assay//Cell proliferation assay |
| Description: | Pretreatment with AEG-1-selective siRNA promoted senescence as indicated by increased β-galactosidase activity in LNCaP and C42B cells treated with toxic concentrations of DIM and ring-DIMs.Our results showed a significant inhibition of cell proliferation in LNCaP and C42B cells pretreated with AEG-1 siRNA and then treated with DIM compared to DMSO control cells. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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