| Gene name: | SOD2 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | Bone |
| Cell name: | Chondrocyte |
| Gene ID: | 6648 |
| Category: | protein coding |
| Phenotype: | Cartilage degeneration |
| Experimental category: | L |
| PMID: | 26108578 |
| Experiment: | Safranin O/Fast Green staining//Flow cytometry |
| Description: | Histological analyses by the OARSI score revealed that Sod2 cKO joints exhibited a significant loss of safranin-O staining in all layers of both articular cartilages in Sod2 cKO mice.The control joint showed the loss of safranin-O staining without morphological changes in the superficial layer of MFC and MTP .Sod2 cKO chondrocytes demonstrated significantly increased superoxide generation via flow cytometry with DHE and MitoSOX stainings. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
Loading,please wait...