| Gene name: | RECQL4 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | Mouse tail |
| Cell name: | Fibroblast |
| Gene ID: | 9401 |
| Category: | protein coding |
| Phenotype: | Rothmund–Thomson syndrome |
| Experimental category: | HL |
| PMID: | 24832598 |
| Experiment: | SA-β-gal activity assay//Immunostaining |
| Description: | Recql4HD fibroblasts expressed more SA-β-gal than wild-type fibroblasts.In addition, the average number of 53BP1 foci was approximately threefold higher under 3%oxygen and fourfold higher under 20% oxygen in cells from old Recql4HDcells compared with cells from old wild-type cells. The average number of γH2A.X foci per cell was two- or threefold more in Recql4HDcells than in wild-type cells. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
Loading,please wait...