| Gene name: | NAMPT |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | IMR-90 |
| Experiment: | SA-β-gal activity assay//Knockdown//Immunostaining |
| Description: | Inhibition of NAMPT by knockdown or by treatment with the small-molecule inhibitor FK86619 suppressed RAS-induced senescence at the time of initiation. Notably, NAMPT upregulation coincided with the upregulation of genes in the second, proinflammatory, SASP wave such as IL1B, IL6 and IL8. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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