| Gene name: | SATB2 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | Bone |
| Cell name: | B-MSC |
| Experiment: | SA-β-gal activity assay//Immunofluorescence |
| Description: | To examine replicative senescence, we repeatedly subcultured T-BMSCs transfected with either Lev-Satb2 or Lev-GFP.We observed that T-BMSCs that overexpressed Satb2 exhibited enhanced anti-aging capacity, as revealed by SA-β-gal staining at the 10th passage.Compared with the Lev-GFP group, the Lev-Satb2 group displayed more intensive GFP staining in both the bone matrix and the surrounding fibroblastic-like tissue, indicating that more exogenous cells survived in the Lev-Satb2 group. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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