| Gene name: | TP73 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | HCT116 |
| Experiment: | SA-β-gal activity assay//Flow cytometry//Knockdown |
| Description: | The senescence-associated β-galactosidase (SA-β-gal) staining showed that p73 knockdown significantly increased the proportion of positive cells (~89.1% in p73i-1 and 79.7% in p73i-2 transfected cells) at 5 dpi, compared to the irradiated controls (~41.2%).However, the proportion of cells in the G2 phase increased significantly in irradiated p73-knockdown cells (30.2% in p73i-1 and 27.2% in p73i-2 transfected cells),compared to that in irradiated control cells (17.8%). |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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