| Gene name: | EIF4EBP1 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | A549,AD32 |
| Experiment: | SA-β-gal activity assay |
| Description: | AD32 cells had a higher basal level of senescence-associated β-galactosidase (SA-β-gal)–positive cells than A549—0.40% and 0.07%, respectively.（AD32 cells have decreased levels of 4E-BP1 mRNA and protein, relative to the parental discodermolide-sensitive A549 cells）. |
| Target gene: | P53 |
| Official symbol(s): | P53 |
| R-AG-Target gene: | Downregulation |
| Subcategory: | Unclear |
| Target gene experiment: | Western blot |
| Target gene description: | AD324E-BP1cells had decreased levels of p53 protein, indicating that p53 levels may be decreased by overexpression of 4E-BP1 in AD32 cells. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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