| Gene name: | DUSP22 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | HS-1 |
| Gene ID: | 56940 |
| Category: | protein coding |
| Phenotype: | Skin cancer |
| Experimental category: | L |
| PMID: | 30536326 |
| Experiment: | Western blot |
| Description: | Transfection of DUSP22 plasmid significantly elevated DUSP22 expression level in HS-1 skin cancer cells,inducing cell aging. Transfection of siRNA DUSP22 significantly depressed DUSP22 expression level in HS-1 skin cancer cells, decreasing expression levels of aging proteins P53 and P21. |
| Regulatory pathway: | MAPK |
| R-AG-Pathway: | Activation |
| Official symbol(s): | MAPK |
| Pathway experiment: | Western blot |
| Pathway description: | Transfection of DUSP22 plasmid significantly elevated DUSP22 expression level in HS-1 skin cancer cells, activating MAPK .Transfection of siRNA DUSP22 significantly depressed DUSP22 expression level in HS-1 skin cancer cells,inhibiting MAPK signal pathway. |
Annotation:
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