| Gene name: | SIRT6 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | KM-HM_(31) |
| Experiment: | SA-β-gal activity assay//Western blot |
| Description: | The increase of Sirtuin 6 apparently up-regulated the expression of P53,however, the block of Sirtuin 6 contributed to the opposite effect on P53 , indicating that Sirtuin 6 participated in CP-induced myeloma cell KM-HM_(31) aging. |
| Regulatory pathway: | HIPPO |
| R-AG-Pathway: | Downregulation |
| Official symbol(s): | hpo |
| Pathway experiment: | Western blot |
| Pathway description: | The increase of Sirtuin 6 apparently reduced the level of Hippo. However, the block of Sirtuin 6 contributed to the opposite effect on Hippo, indicating that Sirtuin 6 might regulate the level of Hippo. |
Annotation:
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