| Gene name: | GPX7 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | OE33,FLO-1 |
| Gene ID: | 2882 |
| Category: | protein coding |
| Phenotype: | Oesophageal adenocarcinoma |
| Experimental category: | L |
| PMID: | 23580780 |
| Experiment: | Growth curve assay//SA-β-gal activity assay//Flow cytometry//Western blot//Colony formation assay |
| Description: | Using stable ( pcDNA-GPX7) and transient reconstitution models of GPX7 in OAC cell lines, we detected a significant reduction in growth rates in GPX7-expressing cells.Our analysis demonstrated that GPX7-expressing OAC cells (OE33 and FLO-1) had a significant increase in β-galactosidase staining (p≤0.01), as compared with control cells.About half of the control cells (Ad-CTRL) had proceeded tothe middle S phase after 4 h while only 32.4% ofGPX7-expressing cells (Ad-GPX7) proceeded to the early S phase. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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