| Gene name: | SIRT1 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | ADSC |
| Experiment: | SA-β-gal activity assay |
| Description: | Cells were treated with SRT1720, a specific SIRT1 activator. Consistent with expected result, SRT1720 decreased the number of SA-βgalimmunopositive cells. |
| Target gene: | P53 |
| Official symbol(s): | P53 |
| R-AG-Target gene: | Downregulation |
| Subcategory: | Acetylation |
| Target gene experiment: | Western blot |
| Target gene description: | p53 protein was decreased by SIRT1 overexpression (pb0.05), suggesting that SIRT1 negatively regulated P53 protein expression. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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