| Gene name: | DNMT3A |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | HCT116 |
| Experiment: | SA-β-gal activity assay//Knockdown |
| Description: | We transfected HCT116 cells with DNMT3a siRNA plasmid, and we found that the number and intensity of SA-β-gal staining cells were increased at 1 lM Dox after DNMT3a was knocked down. |
| Target gene: | P21 |
| Official symbol(s): | P21 |
| R-AG-Target gene: | -- |
| Subcategory: | Unclear |
| Target gene experiment: | Western blot//qRT-PCR |
| Target gene description: | We found that after transfection with DNMT3a siRNA, p21 protein level was upregulated.Transfection of DNMT3a expression plasmid downregulated p21 protein level. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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