| Gene name: | TP53BP2 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | MEF |
| Experiment: | SA-β-gal activity assay |
| Description: | Senescence associated-β-galactosidase (SA-β-gal) activity was detected in around 30% or 41% of cells infected with retroviruses expressing ASPP2 (1–1,128) or ASPP2(1–360), respectively, whereas SAβ-gal activity was not detected in ASPP2(123–1,128)-infected cells. Moreover, rapamycin induced long-lived protein degradation under all conditions, but the most profound increase of about 17-fold was observed in HRAS V12-expressing ASPP2. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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