| Gene name: | ROC1 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | HuH-7,HepG2,LM 6 |
| Gene ID: | 830029 |
| Category: | protein coding |
| Phenotype: | Liver cancer |
| Experimental category: | L |
| PMID: | 22935614 |
| Experiment: | SA-β-gal activity assay//Flow cytometry |
| Description: | In contrast, senescence started to occur at 72 h with continuous increase and reaching the peak at 120 h .SiROC1 induced the G2–M arrest, which occurred at 48?h post ROC1 silencing, and reached a peak at 96?h in HepG2 and Huh7 as well as LM6 cells (data not shown). Morphologically, when compared with control cells, ROC1-silenced cells were much larger in size with flattened shape, a feature of cell senescence. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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