| Gene name: | XPG |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | Embryonic Fibroblast |
| Experiment: | MTT assay//Knockdown |
| Description: | With continuous culture, cells from -/- embryos ceased growing by 4 to 5 weeks after the start of in vitro culture, while cells from the +/+ or +/- embryos kept their growth capability 3 to 4 weeks longer, indicating that -/- cells underwent premature replication senescence,These results indicate that cells from xpg-deficient mice have a short replication life span and readily gain immortality and malignant phenotypes, suggesting that the -/- cells are genetically unstable. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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