| Gene name: | SIRT1 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | PAEC |
| Gene ID: | 23411 |
| Category: | protein coding |
| Phenotype: | Atherosclerosis |
| Experimental category: | HL |
| PMID: | 22753194 |
| Experiment: | SA-β-gal activity assay//Crystal violet assay |
| Description: | Compared to cells transfected with pcDNA vector, the number of senescent cells was reduced significantly in PAECs overexpressing hSIRT1 (by ~42%) or S47A (by ~56%), and the proliferation was enhanced significantly by augmenting either of these two proteins. |
| Target gene: | CDK5 |
| Official symbol(s): | CDK5 |
| R-AG-Target gene: | -- |
| Subcategory: | Unclear |
| Target gene experiment: | -- |
| Target gene description: | -- |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
Loading,please wait...