| Gene name: | DEK |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | HeLa |
| Experiment: | SA-β-gal activity assay |
| Description: | Whereas all of the AdE2ts-infected control cells incubated at the permissive temperature exhibited the characteristically senescent morphology, DEK expression resulted in a mixture of cells with senescent as well as nonsenescent features, indicating partial repression of the E2 senescence phenotype.In agreement with these morphological findings, over 70% of the control cell population were positive for the senescence-specific SA–β-Gal marker at 32°C, with a reduction to 15% upon DEK overexpression. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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