| Gene name: | AKT1 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | U87 |
| Experiment: | SA-β-gal activity assay |
| Description: | The cytoprotective effects of Akt overexpression were associated with a reduction in the percentage of cells expressing senescence-associated β-galactosidase activity at 10 days following temozolomide exposure. |
| Target gene: | CHK2 |
| Official symbol(s): | CHK2 |
| R-AG-Target gene: | -- |
| Subcategory: | Unclear |
| Target gene experiment: | Western blot |
| Target gene description: | U87MG cells expressing the AktERM+ construct, however, exhibited a statistically significant reduction in temozolomide-induced Chk2 phosphorylation (but not in total Chk2 levels) relative to that noted in cells not overexpressing Akt. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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