| Gene name: | AKR1B1 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | Keratinocyte |
| Experiment: | SA-β-gal activity assay//Knockdown |
| Description: | In cells transfected with siRNA against AR or treated with EBPC, this increase in SA β-Gal-positive cells was further enhanced. |
| Target gene: | P53 |
| Official symbol(s): | P53 |
| R-AG-Target gene: | -- |
| Subcategory: | Unclear |
| Target gene experiment: | Knockdown//Western blot |
| Target gene description: | SiRNA-mediated knockdown of AR further increased the elevated expression of p53 induced by UVB radiation, indicating that AR prevents cellular senescence through the regulation of p53 protein expression. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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