| Gene name: | UHRF1 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | 2BS,IMR-90 |
| Experiment: | SA-β-gal activity assay//CCK-8 assay//EdU assay//Knockdown |
| Description: | Cell proliferation rates decreased in UHRF1 shRNA-infected cells. Growth curves of UHRF1 shRNA-infected 2BS cells or IMR9 cells were determined by CCK8 assay.The percentage of cells incorporating EdU also decreased in UHRF1 shRNA-infected 2BS cells or IMR9 cells. SA-β-gal activity staining increased in UHRF1 shRNA-infected cells. Representative microscopic view of 2BS cells or IMR9 cells infected with the indicated vectors with SA-β-gal activity staining. |
| Target gene: | PIM1 |
| Official symbol(s): | PIM1 |
| R-AG-Target gene: | -- |
| Subcategory: | Phosphorylation |
| Target gene experiment: | IP |
| Target gene description: | In reciprocal immunoprecipitations, PIM1 was observed presentingin UHRF1 immunoprecipitates. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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